Guthrie will start Game 3 of the ALCS against the Orioles on Monday, Jon Morosi of FOX Sports reports. Although Guthrie finished the regular season with an uninspiring 4.13 ERA and 1.30 WHIP, he's had success in his career against some of the Orioles' top hitters, namely Adam Jones (1-for-12) and Nelson Cruz (.602 OPS). He's expected to oppose lefty Wei-Yin Chen, though Chen will be available in an emergency Saturday.