Lester announced his retirement from professional baseball Wednesday, Jesse Rogers of ESPN.com reports.

EDGE Analysis

Lester, 38, ends his prolific 16-year MLB career with a 200-117 record, 3.66 ERA and 2,488 strikeouts over 2,740 innings between the Red Sox, Athletics, Cubs, Cardinals and Nationals. He picked up five All-Star nods along the way and was a key rotation piece for World Series-winning teams in Boston (2007 and 2013) and Chicago (2016) while churning out a career 2.51 ERA in the postseason.